Endocrine Abstracts

Introduction: Mild autonomous cortisol secretion (MACS) is a term used to describe biochemical evidence of abnormal cortisol secretion in patients with adrenocortical adenomas (ACA), but without the classical external manifestations of overt Cushing’s syndrome (CS).Materials and Methods: In this study, we report a case of patient who presents mild autonomous cortisol secretion among incidentally discovered adrenal masses; followed in unit of the end...

Introduction: The prevalence of megaloblastic anemia in the adult population is poorly documented, but in the elderly, it has been clearly shown that the prevalence of macrocytic anemia increases after the age of 65 years especially in men. The most frequent etiology of vitamin B12 and folate deficiency is malabsorption. They have an action in the conversion of homocysteine to methionine: an increase in homocysteinaemia is currently considered a cardiovascular risk factor. Str...

Introduction: – The "super bone scan" is a peculiar condition characterized by extremely high bone uptake compared to soft tissue, with no visualization of renal radioactivity.– Super bone scan has been described in relation to several conditions such as metastatic disease (prostate/breast cancer), metabolic bone disease (Paget’s disease/hyperparathyroidism) and myeloproliferative disorders.Clinical Case: – A 75 year old man, ...

Introduction: Cataracts are an opacification of the crystalline lens, either partial or total, primarily caused by senescence, and rarely of metabolic origin. We present the case of a 24-year-old newly diagnosed with bilateral cataracts.Case Presentation: E.S., a 24-year-old with newly discovered diabetes on insulin therapy, presented with a sudden and significant decrease in visual acuity. Ophthalmologic examination revealed bilateral cataracts with an ...

Introduction: Dupuytren’s disease (DD) corresponds to a chronic palpable thickening of the palmar aponeurosis which leads to different degrees of irreducible flexion of the fingers. It is one of the manifestations of hand syndrome in diabetes mellitus. We highlight through this report the occurrence of DD as a manifestation of diabetic hand syndrome in a patient with type 2 diabetes mellitus.Observation: A sixty-six year old patient, truck driver, t...

Introduction: Mauriac syndrome (MS) is a rare complication of type 1 diabetes mellitus (DM1), characterized by hepatomegaly (hepatic glycogenosis), puberty and growth delay, transaminase elevation and reduction of IGF1 (insulin-like growth factor 1). MS is more common in children and adolescents with poor glycemic control.Case Report: A 17-years-old Type 1 diabetic boy was admitted for evaluation of growth retardation. He was diagnosed to have T1DM 15 ye...

Introduction: Research in the past two decades has shown that Fenugrec seeds help to lower blood glucose in patients with diabetes. Its role as an antidiabetic, by reducing fasting blood glucose levels and improved glucose tolerance in human subjects was reported Curcuminoids have been shown to improve insulin resistance, decrease glucose and insulin levels, increase adiponectin release, and reduce the levels of leptin, resistin, interleukin (IL)-6 IL-1b, and tumor necrosis fa...

Introduction: Type 2 diabetes is an important risk factor for all forms of infection. It may be unrecognised for many years, and often revealed by degenerative or infectious complications. The aim of this study is to investigate the epidemiological, clinical and therapeutic aspects of severe infections revealing type 2 diabetes.Patients and Methods: Retrospective descriptive cross-sectional study of a series of 5 patients with severe infections revealing...

Introduction: Benzold abscess remains rare, and its occurrence implies immunosuppression, particularly within unbalanced diabetes.Methods and Results: Observation of a 76-year-old patient, diabetic for 29 years, on metformin, admitted for CMO of the right ear, complicated by Bezold’s abscess. The interrogation revealed purulent otorrhea hypoacusis. The clinical examination revealed hyperglycemia, a swelling of the sternocleidomastoid, responsible fo...

Introduction: Digital necrosis of the upper limbs is the final and often the only clinical manifestation of a of a distal arterial or microcirculatory pathology of the MS. The approach to The approach to this condition is very different, hence the particularity of our observation which highlights the severity of vascular lesions found in diabetic patients.Observation: This is a 58 year old diabetic patient on mixtard 30: 16-00-08 ui; schizophrenia; on cl...